Structure and Function of Membrane Proteins

Prof. Dr. Joachim Heberle, Exp. Molecular Biophysics, FU Berlin, Germany

 "My lab focuses on the elucidation of the structure and function of membrane proteins. This topic includes the investigation of protein-protein and protein-substrate interactions. We are employing MST in binding studies of membrane sensors to their transducers as well as soluble transcription factors to DNA. We also plan for investigations of receptor - ligand interactions with this exciting new technique. MST turned out to be an extremely useful method in our lab to determine binding constants. It is advantageous that the fast and handy experiments require only few amounts of protein."

Prof. Joachim Heberle