miRNA Biogenesis in Drosophilia

Prof. Dr. Klaus Förstemann, Gene Center of the LMU, Munich, Germany

 "We are studying the processing of microRNA precursors In Drosophila and are using MST to measure the binding of nucleolytic Enzymes and their specificity factors to RNA substrates. The small amount of protein sample needed and the much faster measuring time compared with e.g. gel-shift assays are particular strengths of this new technique. It enables us to ask questions that we could not address before." 

Prof. Klaus Förstemann